1. Каталог >
  2. Реактивы >
  3. Виды реактивов >
  4. Клик-химия >
  5. Клик-химия по хим.составу >

Метилциклопропен - моносахариды

Methylcyclopropene Reagents - Monosaccharides

Methylcyclopropene-containing monosaccharides can be used to attach methylcyclopropene groups to glycoconjugates via metabolic labeling [1-3] followed by subsequent labeling with Tetrazine-containing detection reagents via Cu(I)-free Tetrazine-Cyclopropene Ligation. [4]

A number of CLICKable monosaccharides are available for metabolic glycan labeling.
Описание в PDF
Datasheet
НазваниеКодЦена Количество
5 mg pack CLK-042-5 по запросу 5 mg



Datasheet
НазваниеКодЦена Количество
5 mg pack CLK-041-5 по запросу 5 mg





Selected References
[1] Spaete et al. (2014) Expanding the scope of cyclopropene reporters for the detection of metabolically engineered glycoproteins by Diels–Alder reactions. Beilstein J. Org. Chem. 10:2235.
[2] Spaete et al. (2014) Rapid labeling of metabolically engineered cell-surface glycoconjugates with a carbamate-linked cyclopropene reporter. Bioconj. Chem. 25:147.
[3] Patterson et al. (2014) Improved cyclopropene reporters for probing protein glycosylation. Mol. BioSyst.10:1693.
[4] Patterson et al. (2012) Functionalized cyclopropenes as bioorthogonal chemical reporters. J. Am. Chem. Soc. 134:18643.

Информация представлена исключительно в ознакомительных целях и ни при каких условиях не является публичной офертой