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Anti-IFN-α: Monoclonal Interferon-alpha Antibody


BACKGROUND Interferon (IFN)-alpha and IFN-beta are critical mediators of host defense against microbial challenges, directly interfering with viral infection and influencing both the innate and adaptive immune responses. IFNs exert their effects in target cells through the activation of a cell-surface receptor, leading to a cascade of signaling events that determine transcriptional and translational regulation.1 Recombinant human IFN-alpha was the first biotherapeutic agent approved by the US Food and Drug Administration for the treatment of a human malignancy. Its efficacy has also been demonstrated for treatment of several viral diseases including hepatitis.2,3
 
REFERENCES  
1. Galligan, C.L. et al., Immunol. Res. 35:27, 2006.
2. Masci, P. et al., Curr. Oncol. Rep. 5:108, 2003.
3. Bukowaski, R. M. et al., Cancer 95:389, 2002.
 
Products are for research use only. They are not intended for human, animal, or diagnostic applications.

Параметры

Cat.No.:
CB10256
Antigen:
Recombinant human interferon-alpha protein
Isotype:
Mouse Monoclonal IgG1
Species & predicted
species cross-
reactivity ( ):
Human
Applications &
Suggested starting
dilutions:
WB                  1:1000
IP                    n/d
IHC                  n/d
ICC                  n/d
FACS               n/d
Predicted Molecular
Weight of protein:
19 kDa
Specificity/Sensitivity:
Anti-IFN-alpha reacts specifically with human IFN-alpha in Western Blot applications.
Storage:
-20°

*Optimal working dilutions must be determined by end user.



Документы



НазваниеКодЦена
Monoclonal Anti-IFN-alpha Mouse Antibody CB10256 по запросу




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