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Rat Schwann Cells: RSC

Rat Schwann Cells: RSC

Rat Schwann Cells (RSC) are the principle glial cells in the peripheral nervous system, providing physical and chemical supports for neurons.  Myelinating Schwann cells surround neuronal cell bodies (sensory ganglia) and fibers (sensory and motor neurons) to form an insulating sheath. Periodic exposure of the axonal membrane to the extracellular space at the nodes of Raniver (myelin sheath gaps) allows rapid propagation of action potentials along the axon.  RSC are important for morphology, survival and growth of axons & neurons.  Studies also indicate Schwann cells promote neuronal restoration and experimental spinal cord regeneration.
The calcium binding protein S100β, a marker present in cultured Schwann cells, participates in paracrine mechanisms and neuronal maintenance.  S100β exerts neurotrophic effects to both peripheral sensory and motor neurons, and demonstrates experimental promise to repair, restore or treat nerve injuries and CNS lesions.
Characterization: Rat Schwann Cells from every lot stain Positive for S100β, attach & spread on tissue culture ware and proliferate in Rat Schwann Cell Growth Medium.


Rat Schwann Cells: RSC

TissueNormal healthy adult rat peripheral nerves
QCNo bacteria, yeast, fungi, mycoplasma
CharacterPositive for S100β
BioassayAttach, spread, proliferate in Gr Med
Cryovial500,000 RSC (1st passage) frozen in Basal Medium w/ 10% FBS, 10% DMSO
KitCryovial frozen RSC (R842-05a), Growth Medium (R826-500), Subcltr Rgnt Kit (090K)
ProliferatingShipped in Gr Med, 1st psg (flasks or plates)
DoublingsAt least 3


Rat Schwann Cells: RSC

Frozen RSC R842-05a по запросу

Cells, Medium & Subculture Reagents (See Details tab for specifics) R842K-05a по запросу

Actively growing, dividing cells in medium R843-6Wa по запросу
Actively growing, dividing cells in medium R843-75a по запросу
Actively growing, dividing cells in medium R843-96Wa по запросу
Actively growing, dividing cells in medium R843-25a по запросу

Extended Family Products

Mouse S100B Antibody CP10223 по запросу

For general cryopreservation of most primary cells. Contains FBS & DMSO. 040-50 по запросу

100 tests 028-S по запросу
500 tests 028-01 по запросу

100 ml each of HBSS, Trypsin/EDTA & Trypsin Neutralizing Solution 090K по запросу

Related Products

Basal medium (contains no growth supplement). Add GS before use. R825-500 по запросу

All-in-one ready-to-use media R826-500 по запросу

Basal medium & growth supplement sold together packaged separately R826K-500 по запросу

Added to Basal Medium to create Growth Medium R826-GS по запросу

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